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Independently verified key components of the green tea extract batch GTE50-A0302031114 were polyphenols, catechins, gallates, caffeine, moisture, ash, heavy metals and residues, and these results suggest that green tea extract compounds may downregulate or suppress CYP1A2, 2E1, and 3A4 reduce APAP conversion to the reactive metabolite NAPQI

doi:10.3389/fmicb.2019.00050 T?zsrJ, Benk

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[DOI] [PubMed] [Google Scholar] Malagutti KS, da Silva AP, Braga HC, Mitozo PA, Soares dos Santos AR, Dafre AL, de Bem AF, Farina M

42 The surviving BC cells can then exploit astrocytes through communication via gap junctions composed of connexin 43 (Cx43) and protocadherin 7 (PCDH7) to gain benefits in terms of growth, chemoresistance, stemness and autophagy

The last observation strongly supports that K l-la is caused by an enzyme-mediated process and not uncatalyzed chemical reactions such as the formation of K d-la and K ce from LGSH and MGO, because the chemical reaction could be more random among the genomic regions